New Developments

After licensure of the 7-valent pneumococcal conjugate vaccine (PCV7) in the United States in 2000, the incidence of pediatric pneumococcal meningitis decreased significantly. However, cases continue to occur. In this study, laboratory-confirmed pneumococcal meningitis among Utah children from 1997 to 2010 performed and medical records and obtained clinical data during the acute illness and follow-up data on neurologic sequelae reviewed. This study was a cohort study of laboratory-confirmed pneumococcal meningitis among Utah children from 1997 to 2010.  After reviewing the...

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On June 28, 2013, CDC was notified of 2 laboratory-confirmed cases of Cyclospora infection in Iowa residents who had become ill in June and did not have a history of international travel during the 14 days before the onset of illness. Since that date, CDC has been collaborating with public health officials in multiple states and the U.S. Food and Drug Administration (FDA) to investigate an outbreak of cyclosporiasis. On June 28, 2013, CDC was notified of 2 laboratory-confirmed cases...

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The incidence of dengue has grown dramatically around the world in recent decades.  Over 2.5 billion people – over 40% of the world's population – are now at risk from dengue.  In recent years, transmission has increased predominantly in urban and semi-urban areas and has become a major international public health concern. This updated fact sheet provides several concrete ways to combat the dengue-carrying mosquitoes, which is the only way to prevent transmission of the virus. http://www.who.int/mediacentre/factsheets/fs117/en/index.html Haber: Hamdi Sözen...

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As of 15May 2013, 24 cases of Nipah virus infection have been reported in Bangladesh since the beginning of 2013, of which 21 cases have died. The Nipah virus was first identified in 1999 during an outbreak among pig farmers in Malaysia. Since then, there have been more than 12 outbreaks, all in South Asia. Transmission is caused by the consumption of the raw sap of a date palm tree which has been contaminated with urine or saliva from infected...

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"Infection risk at New Brunswick hospital affects nearly 2,500 women colposcopy clinic didn't always follow sterilization rules for biopsy forceps over 14 years" CBC News Posted: Aug 28, 2013 11:56 AM AT Last Updated: Aug 28, 2013 7:03 PM AT http://www.cbc.ca/news/canada/new-brunswick/story/2013/08/28/nb-miramichi-colposcopy-infection.html Haber: Vedat Turhan Posted September 11, 2013

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This study is conducted in Van, and aimed to identify the Brucella strains from the collected clinical samples of the patients with brucellosis in Western Anatolia region, and look for tigecycline and azithromycin sensitivity in order to define alternative treatment regimens to the convencional drugs. The 75 isolates included in the study are identified by both conventional and molecular methods and antibiotic sensitivity is determined by E-test. As a result; the drugs used in the treatment brucellosis such as doxycycline,...

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Group B Streptococcus (GBS) is a major cause of morbidity and mortality among neonates. Though there have been tremendous advances in prevention of invasive neonatal GBS disease through prophylactic antibiotic treatment of pregnant women, the incidence of neonatal disease has not changed significantly over the past several years. Vaccination of pregnant women is an important strategy that has the potential to improve further on existing protocols. In this review, we explore the history of the design of maternal GBS vaccines. Chen et...

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The index case, confirmed by the Uganda Virus Research Institute, is a male farmer from Baroma village in Atece Parish in Omot sub-county. He fell ill on 8 August 2013,   presenting   with high fever, general body weakness, muscle pain and bleeding from some body parts. On 10 August, he was admitted to Kalongo Hospital in Agago district where he is currently receiving treatment. In addition, three people in the affected area have reportedly died with similar symptoms.  These deaths are...

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The U.S. Food and Drug Administration (FDA) is warning the public that azithromycin  can cause abnormal changes in the electrical activity of the heart that may lead to a potentially fatal irregular heart  rhythm. Patients at particular risk for developing this condition include those with known risk factors such as existing QT interval prolongation, low blood levels of potassium or magnesium, a slower than normal heart rate, or use of certain drugs used to treat arrhythmias. http://www.fda.gov/drugs/drugsafety/ucm341822.htm

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This was a multicentre, retrospective observational study (2005-11). Seventy patients met the inclusion criteria and comprised 33 (47.1%) with right-sided IE (RIE), 35 (50%) with left-sided IE (LIE) and 2 with both RIE and LIE. Sixty-five patients received daptomycin as salvage therapy. For those patients with pathogens isolated (n = 64), the organism was eradicated in 57 (89.1%) patients. Among 64 clinically evaluable patients, 55 (85.9%) achieved clinical success. No patients required discontinuation of high-dose daptomycin due to creatine phosphokinase elevations. http://jac.oxfordjournals.org/content/early/2013/08/07/jac.dkt294.full.pdf...

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