Mysterious New Mosquito-Borne Disease Found in Caribbean

Mysterious New Mosquito-Borne Disease Found in Caribbean http://www.genengnews.com/gen-news-highlights/mysterious-new-mosquito-borne-disease-found-in-caribbean/81253208/ Physicians in Haiti and researchers from the University of Florida (UF) have stumbled upon a patient infected with a rare virus that until recently has been confined to small outbreaks in the Amazon. Known as Mayaro virus, this pathogen belongs to the Alphavirus genus, is closely related to chikungunya, and produces a dengue-like illness that is often accompanied by long-lasting arthralgia (joint pain). Whether this case signals the start of a new...

Devamı/Read More

Is it Really a Penicillin Allergy?

Evaluation and Diagnosis of Penicillin Allergy for Healthcare Professionals Did You Know? 5 Facts About Penicillin Allergy (Type 1, Immunoglobulin E (IgE)-mediated)   http://www.cdc.gov/getsmart/week/downloads/getsmart-penicillin-factsheet.pdf     PDF Download

Devamı/Read More

Comparative Effectiveness of Ledipasvir/Sofosbuvir ± Ribavirinvs. Ombitasvir/Paritaprevir/Ritonavir + Dasabuvir ± Ribavirin in 6961 Genotype 1 Patients Treated in Routine Medical Practice

L. I. Backus; P. S. Belperio; ; T. A. Shahoumian; T. P. Loomis; L. A. Mole Aliment Pharmacol Ther. 2016;44(4):400-410.  http://www.medscape.com/viewarticle/866290?nlid=109253_804&src=WNL_mdplsfeat_160913_mscpedit_infd&uac=177387BK&spon=3&impID=1196211&faf=1 Abstract and Introduction Abstract Background Real-world data are needed to inform hepatitis C virus (HCV) treatment decisions. Aim To assess the comparative effectiveness of ledipasvir/sofosbuvir ± ribavirin (LDV/SOF ± RBV) vs. ombitasvir/paritaprevir/ritonavir + dasabuvir (OPrD) ± RBV in genotype 1 HCV patients treated in routine medical practice. Methods Observational intent-to-treat cohort of genotype 1 patients initiating 8 or 12 weeks...

Devamı/Read More

Antibacterials in Dust May Contribute to Antibiotic Resistance

Just days after the FDA ruled that antimicrobials are to be removed from liquid and bar soaps, yet more suspicion is falling on antibacterial ingredients, which are exempt from the upcoming ban, provided they occur in other products, such as paints, baby toys, bedding, and kitchen utensils. Antimicrobials have been found in indoor dust, along with antibiotic-resistance genes. Moreover, six significant positive associations have been observed between the concentration of an antimicrobial chemical and the relative abundance of an antibiotic-resistance...

Devamı/Read More

Helicobacter pylori Treatment: The ‘Rules’ Have Changed

http://www.medscape.com/viewarticle/867932?nlid=109145_804&src=WNL_mdplsfeat_160906_mscpedit_infd&uac=177387BK&spon=3&impID=1192238&faf=1 Hello. I am Dr David Johnson, professor of medicine and chief of gastroenterology at Eastern Virginia Medical School in Norfolk, Virginia. Helicobacter pylori treatment has changed the natural history of peptic disease in this country and around the world. In addition, such treatment has affected other consequences of H pylori, in particular some of the mucosa-associated lymphoid tissue (or MALT) lymphomas and other specific disease categories that benefit from its eradication. But the treatment has changed. Years ago, when...

Devamı/Read More

Polio in the Syrian Arab Republic

29 October 2013 - Following reports of a cluster of 22 acute flaccid paralysis (AFP) cases on 17 October 2013 in the Syrian Arab Republic, wild poliovirus type 1 (WPV1) has been isolated from ten of the cases under investigation. Final genetic sequencing results are pending to determine the origin of the isolated viruses. Wild poliovirus had not been detected in the Syrian Arab Republic since 1999. Most of the cases are very young (below two years of age), and...

Devamı/Read More

Hazard of Suicidality in Patients Randomly Assigned to Efavirenz for Initial Treatment of HIV-1: a Cross-Study Analysis Conducted by the AIDS Clinical Trials Group (ACTG)

Background: Efavirenz (EFV) is widely used for the treatment of HIV, but there is some uncertainty regarding its relationship to suicidality.  Here we examine the effect of initial treatment with an EFV-containing versus EFV-free regimen on the risk of suicidality. Methods:   Data from four ACTG studies (A5095, A5142, A5175, A5202) of antiretroviral-naïve participants enrolled from 2001-2007 were included. Participants in each trial were randomized to EFV-containing or EFV-free (protease inhibitor or 3-nucleoside) regimens; assignment to EFV was open label...

Devamı/Read More

First Outbreak Response Using an Oral Cholera Vaccine in Africa

Author Summary Two safe and effective oral cholera vaccines are recommended by the World Health Organization for cholera prevention and control; however, concerns about the acceptability, potential diversion of resources, cost and feasibility of implementing timely campaigns has discouraged their use. In 2012, the Ministry of Health of Guinea, with the support of Médecins Sans Frontières, organized the first mass vaccination campaign using a two-dose oral cholera vaccine (Shanchol) as an additional control measure to respond to an on-going nationwide...

Devamı/Read More

Eurosurveillance is indexed in Science Citation Index Expanded

Eurosurveillance is indexed in PubMed/MEDLINE, Scopus, EMBASE and EBSCO databases. The journal has been selected for coverage by Thomson Reuters and is indexed and abstracted in the Science Citation Index Expanded (also known as SciSearch) and in the Journal Citation Reports/Science Edition beginning with Volume 14(1) 2009. The current impact factor, for the year 2012, is 5.491 (Journal Citation Reports, Thomson Reuters, 2013). This places Eurosurveillance at rank 6 among the 69 journals in the category Infectious Diseases. http://www.eurosurveillance.org/Public/AboutUs/AboutUs.aspx

Devamı/Read More